Ana Lima is an experienced PI researcher with expertise in agronomy, food engineering, and One Health. She currently serves as an Assistant Professor and the Research Coordinator at the FMV-ULusófona. She has a MsC in Toxicology, a PhD in Biology, and completed her post-doc in Food Biochemistry. She is the Head of the Food Safety and Bioactivities Group at the FMV-ULusófona and the vice-director of the research unit I-MVET from Lusófona University. She has participated in more than 25 national and European projects and was PI of 5. She has supervised numerous students at various academic levels and has 122 publications, of which 60 are peer-reviewd papers. She received the Born from Knowledge Award in 2018 for her contributions to food innovation and holds three international patents for her discoveries in functional foods.
Freitas, R.; Costa, E.; Velez, C.; Santos, J.; Lima, A.; Oliveira, C.; Maria Rodrigues, A.; Quintino, V.; Figueira, E.. (2012). Looking for suitable biomarkers in benthic macroinvertebrates inhabiting coastal areas with low metal contamination: Comparison between the bivalve Cerastoderma edule and the Polychaete Diopatra neapolitana. http://www.scopus.com/inward/record.url?eid=2-s2.0-80655127691&partnerID=MN8TOARS
Direito, Rosa; Lima, Ana; Rocha, João; Ferreira, Ricardo Boavida; Mota, Joana; Rebelo, Patrícia; Fernandes, Adelaide; et al. (2017). Dyospiros kaki phenolics inhibit colitis and colon cancer cell proliferation, but not gelatinase activities. http://dx.doi.org/10.1016/j.jnutbio.2017.03.002
Lima, A.I.G.; Mota, J.; Monteiro, S.A.V.S.; Ferreira, R.M.S.B.. (2016). Legume seeds and colorectal cancer revisited: Protease inhibitors reduce MMP-9 activity and colon cancer cell migration. http://dx.doi.org/10.1016/j.foodchem.2015.10.063
Lima, Ana; Oliveira, Jennifer; Saúde, Filipe; Mota, Joana; Ferreira, Ricardo. (2017). Proteins in Soy Might Have a Higher Role in Cancer Prevention than Previously Expected: Soybean Protein Fractions Are More Effective MMP-9 Inhibitors Than Non-Protein Fractions, Even in Cooked Seeds. http://dx.doi.org/10.3390/nu9030201
Santos, Maria I.S.; Lima, Ana I.; Monteiro, Sara A.V.S.; Ferreira, Ricardo M.S.B.; Pedroso, Laurentina; Sousa, Isabel; Ferreira, Maria A.S.S.. (2016). Preliminary Study on the Effect of Fermented Cheese Whey on Listeria monocytogenes, Escherichia coli O157:H7, and Salmonella Goldcoast Populations Inoculated onto Fresh Organic Lettuce. http://dx.doi.org/10.1089/fpd.2015.2079
Santos, M. I. S.; Martins, S. R.; Veríssimo, C. S. C.; Nunes, M. J. C.; Lima, A. I. G.; Ferreira, R. M. S. B.; Pedroso, L.; Sousa, I.; Ferreira, M. A. S. S.. (2017). Essential oils as antibacterial agents against food-borne pathogens: Are they really as useful as they are claimed to be?. http://dx.doi.org/10.1007/s13197-017-2905-0
Santos, M.I.S.; Fradinho, Patrícia; Martins, S.; Lima, Ana; Ferreira, Ricardo Boavida; Pedroso, L.; Ferreira, M.A.S.S.; Sousa, I.. (2020). A Novel Way for Whey: Cheese Whey Fermentation Produces an Effective and Environmentally-Safe Alternative to Chlorine.
Mota, Joana; Lima, Ana; B. Ferreira, Ricardo; Raymundo, Anabela. (2020). Lupin Seed Protein Extract Can Efficiently Enrich the Physical Properties of Cookies Prepared with Alternative Flours. http://dx.doi.org/10.3390/foods9081064
Graça, Carla; Mota, Joana; Lima, Ana; Boavida Ferreira, Ricardo; Raymundo, Anabela; Sousa, Isabel. (2020). Glycemic Response and Bioactive Properties of Gluten-Free Bread with Yoghurt or Curd-Cheese Addition. http://dx.doi.org/10.3390/foods9101410
Oliveira, Isabel; Nunes, António; Lima, Ana; Borralho, Pedro; Rodrigues, Cecília; Ferreira, Ricardo; Ribeiro, Ana. (2019). New Lectins from Mediterranean Flora. Activity against HT29 Colon Cancer Cells. http://dx.doi.org/10.3390/ijms20123059
Lima, Ana; Batista-Santos, Paula; Veríssimo, Eduarda; Rebelo, Patrícia; Ferreira, Ricardo Boavida. (2020). Differential inhibition of gelatinase activity in human colon adenocarcinoma cells by Aloe vera and Aloe arborescens extracts. http://dx.doi.org/10.1186/s12906-020-03134-9
Rocha, João; Direito, Rosa; Lima, Ana; Mota, Joana; Gonçalves, Margarida; Duarte, Maria Paula; Solas, João; et al. (2019). Reduction of inflammation and colon injury by a Pennyroyal phenolic extract in experimental inflammatory bowel disease in mice. http://dx.doi.org/10.1016/j.biopha.2019.109351
Direito, Rosa; Rocha, João; Lima, Ana; Gonçalves, Maria Margarida; Duarte, Maria Paula; Mateus, Vanessa; Sousa, Catarina; et al. (2019). Reduction of Inflammation and Colon Injury by a Spearmint Phenolic Extract in Experimental Bowel Disease in Mice. http://dx.doi.org/10.3390/medicines6020065
Lima, Ana. (2021). An Up-Scalable and Cost-Effective Methodology for Isolating a Polypeptide Matrix Metalloproteinase-9 Inhibitor from Lupinus albus Seeds. https://doi.org/10.3390/foods10071663
Lima, Ana. (2021). Mota J, Ferreira RB, Raymundo A, Lima A. (2021). Development of a lupin protein concentrate as a nutraceutical delivery system for addition to cancer-preventing foods..
Lima, Ana. (2021). M. I. S. Santos, A. I. G. Lima, J. Mota, P. Rebelo, R. M. S. B. Ferreira, L. Pedroso, I. Sousa (2021). Extended fermentation produces a broad-range antibacterial peptide that also targets matrix metalloproteases related to inflammation and cancer. .
Mota, Joana; Direito, Rosa; Rocha, João; Fernandes, João; Sepodes, Bruno; Figueira, Maria Eduardo; Raymundo, Anabela; Lima, Ana; Ferreira, Ricardo Boavida. (2021). Lupinus albus Protein Components Inhibit MMP-2 and MMP-9 Gelatinolytic Activity In Vitro and In Vivo. http://dx.doi.org/10.3390/ijms222413286
Carla Graça; Ana Lima; A. Raymundo; Isabel Sousa. (2021). Sourdough Fermentation as a Tool to Improve the Nutritional and Health-Promoting Properties of Its Derived-Products. https://www.mdpi.com/2311-5637/7/4/246
Maria Isabel Santos; Ana Lima; Joana Mota; Patrícia Rebelo; Ricardo Boavida Ferreira; Laurentina Pedroso; Maria Adélia Ferreira; Isabel Sousa. (2021). Extended Cheese Whey Fermentation Produces a Novel Casein-Derived Antibacterial Polypeptide That Also Inhibits Gelatinases MMP-2 and MMP-9. https://www.mdpi.com/1422-0067/22/20/11130
João Carlos Fernandes; Elizângela G. Schemitt; da Silva, Juliana; da Silva, J.; da silva, j.; dasilva, j.; silva, jd; silva j.; Silva, J. D.; Silva, j.d.; Norma P. Marroni; Ana Lima; Ricardo B. Ferreira. (2021). Combination of Trans-Resveratrol and e-Viniferin Induces a Hepatoprotective Effect in Rats with Severe Acute Liver Failure via Reduction of Oxidative Stress and MMP-9 Expression. https://www.mdpi.com/2072-6643/13/11/3677
Joana Mota; Sandra Casimiro; João Carlos Fernandes; Renata M. Hartmann; Elizângela Schemitt; Jaqueline Picada; Luis Costa; et al. (2022). Lupin Protein Concentrate as a Novel Functional Food Additive That Can Reduce Colitis-Induced Inflammation and Oxidative Stress. https://www.mdpi.com/2072-6643/14/10/2102
Rute Canejo-Teixeira; Ana Lima; Ana Santana. (2022). Applications of Contrast-Enhanced Ultrasound in Splenic Studies of Dogs and Cats. https://doi.org/10.3390/ani12162104
Duarte, Carla Margarida; Mota, Joana; Assunção, Ricardo; Martins, Carla; Ribeiro, Ana Cristina; Lima, Ana; Raymundo, Anabela; et al. (2022). New Alternatives to Milk From Pulses: Chickpea and Lupin Beverages With Improved Digestibility and Potential Bioactivities for Human Health. http://dx.doi.org/10.3389/fnut.2022.852907
Sara Silva; Ana Cavaco; Bianca Basso; Joana Mota; Raquel Cruz-Duarte; Miguel Costa; Lara Carvalho; et al. (2022). Therapeutic Potential of Deflamin against Colorectal Cancer Development and Progression. https://doi.org/10.3390/cancers14246182
Santos, Maria Isabel S.; Marques, Cátia; Mota, Joana; Pedroso, Laurentina; Lima, Ana. (2022). Applications of Essential Oils as Antibacterial Agents in Minimally Processed Fruits and Vegetables—A Review. http://dx.doi.org/10.3390/microorganisms10040760
Lima, Ana; Isabel Santos. (2023). Milk's Bioactive Peptides: Are We Disregarding Nature's Miracle?. DOI: 10.31031/NTNF.2023.07.000651
Maria Isabel Santos; Madalena Grácio; Mariana Camoesas Silva; Laurentina Pedroso; Ana Lima. (2023). One Health Perspectives on Food Safety in Minimally Processed Vegetables and Fruits: From Farm to Fork. https://doi.org/10.3390/microorganisms11122990
Joana Ferreira; Karolina Tkacz; Igor Piotr Turkiewicz; Maria Isabel Santos; Adriana Belas; Ana Lima; Aneta Wojdylo; Isabel Sousa. (2023). Influence of Particle Size and Extraction Methods on Phenolic Content and Biological Activities of Pear Pomace. https://doi.org/10.3390/foods12234325
Grácio, Madalena; Oliveira, Sabrina; Lima, Ana; Boavida Ferreira, Ricardo. (2023). RuBisCO as a protein source for potential food applications: A review. https://doi.org/10.1016/j.foodchem.2023.135993
Alegria, Sandy J.C.; Santos, Maria Isabel S.; Furtado, Rosália M.S.; Correia, Cristina Belo; Lima, Ana; Pedroso, Laurentina R.; Ramos, Sónia Catarina da Silva. (2022). Assessment of the Microbiological Quality and Safety in Takeaway Sushi Meals in Portugal. http://dx.doi.org/10.1159/000525005
S. Santos, Maria; Fradinho, Patrícia; Martins, Sandro; Lima, Ana; M. S. Boavida Ferreira, Ricardo; Pedroso, Laurentina; S. S. Ferreira, Maria; Sousa, Isabel. (2019). A Novel Way for Whey: Cheese Whey Fermentation Produces an Effective and Environmentally-Safe Alternative to Chlorine. http://dx.doi.org/10.3390/app9142800
Isabel Santos; Mariana Silva; Madalena Grácio; Laurentina Pedroso; Ana Lima. (2024). Milk Antiviral Proteins and Derived Peptides against Zoonoses. https://doi.org/10.3390/ijms25031842
Saeed Salari; Joana Ferreira; Ana Lima; Isabel Sousa. (2024). Effects of Particle Size on Physicochemical and Nutritional Properties and Antioxidant Activity of Apple and Carrot Pomaces. https://doi.org/10.3390/foods13050710
Elia Ana Baltazar-García; Belinda Vargas-Guerrero; Ana Lima; Ricardo Boavida Ferreira; María Luisa Mendoza-Magaña; Mario Alberto Ramírez-Herrera; Tonatiuh Abimael Baltazar-Díaz; et al. (2024). Deflamin Attenuated Lung Tissue Damage in an Ozone-Induced COPD Murine Model by Regulating MMP-9 Catalytic Activity. https://doi.org/10.3390/ijms25105063
Mota, Joana; Direito, Rosa; Rocha, João; Fernandes, João; Sepodes, Bruno; Figueira, Maria Eduardo; Raymundo, Anabela; Lima, Ana; Ferreira, Ricardo Boavida. (2021). Lupinus albus protein componentes inhibit MMP-2 and MMP-9 gelatinolytic activity in vitro and in vivo. http://hdl.handle.net/10400.5/22755
Salari, Saeed; Ferreira, Joana; Lima, Ana; Sousa, Isabel. (2024). Effects of Particle Size on Physicochemical and Nutritional Properties and Antioxidant Activity of Apple and Carrot Pomaces. http://dx.doi.org/10.3390/foods13050710
Saeed Salari; Thomas Castigliego; Joana Ferreira; Ana Lima; Isabel Sousa. (2024). Development of Healthy and Clean-Label Crackers Incorporating Apple and Carrot Pomace Flours. https://doi.org/10.3390/su16145995
Tomás Moita; Laurentina Pedroso; Isabel Santos; Ana Lima. (2025). Casein and Casein-Derived Peptides: Antibacterial Activities and Applications in Health and Food Systems. https://doi.org/10.3390/nu17101615
Ferreira, Joana; Tkacz, Karolina; Turkiewicz, Igor Piotr; Santos, Isabel; Camoesas e Silva, Mariana; Lima, Ana; Sousa, Isabel. (2024). Exploring the Bioactive Properties and Therapeutic Benefits of Pear Pomace. https://doi.org/10.3390/antiox13070784
Salari, Saeed; Castigliego, Thomas; Ferreira, Joana; Lima, Ana; Sousa, Isabel. (2024). Development of Healthy and Clean-Label Crackers Incorporating Apple and Carrot Pomace Flours. https://doi.org/10.3390/su16145995
Canejo-Teixeira, Rute; Carvalho, Mariana; Semião Teixeira, Gil; Lima, Ana; Crowell, Chris; Kwok, Jack; Lulich, Jody; Kirpensteijn, Jolle; Grosso, Federico Vilaplana. (2025). A Pilot Study on Using an Artificial Intelligence Algorithm to Identify Urolith Composition through Abdominal Radiographs in the Dog. https://doi.org/10.1111/vru.70012
Veríssimo, Cristina; Toscano, Cristina; Ferreira, Teresa; Abreu, Gabriela; Simões, Helena; Diogo, José; Queirós, Ana Maria; et al. (2019). Etiologia das infeções fúngicas invasivas e subcutâneas: análise dos dados da Rede Nacional de Vigilância Laboratorial das Infeções Fúngicas Invasivas e Subcutâneas (IFIs), 2013-2018. http://hdl.handle.net/10400.18/6393
Tomaz, Alexandra; Palma, Patrícia; Fialho, Sofia; Lima, Ana; Alvarenga, Paula; Potes, Miguel; Salgado, Rui. (2020). Spatial and temporal dynamics of irrigation water quality under drought conditions in a large reservoir in Southern Portugal. http://dx.doi.org/10.1007/s10661-019-8048-1
Lima, Ana. (2026). Impacto do treino de obediência no estado emocional do cão durante uma consulta veterinária de rotina: resultados preliminares. Thalita Rosa Rocha, Raquel Matos, Ana Lima, Tiago Mendonça.. 12https://doi.org/10.60543/rlcmv.v20i.11084
Lima, Ana. (2026). - Production of bioactive peptides through fermentation. Tomás Moita, Adriana Belas, Laurentina Pedroso, Ana Lima, Isabel Santos. Revista Lusófona de Ciência e Medicina Veterinária, v. 20 (2026), IV Encontro de Investigação da FMV da Universidade Lusófona- Edição Especial, pp. 16. .
Lima, Ana. (2026). - DNA Extraction from Equine Feces for Microbiome Studies – Optimization Challenges Inês Rolo, Inês Chambino, Ana Lima, Gesiane Ribeiro, Ricardo Agrícola, Tiago Mendonça, José Prazeres, Adriana Belas. Revista Lusófona de Ciência e Medicina Veterinária, v. 20 (2026), IV Encontro de Investigação da FMV da Universidade Lusófona- Edição Especial, pp. 34. .
Lima, Ana. (2026). Establishment of In Vitro 2D Cell Cultures and 3D Organoids from Canine Intestinal Tumor. Catarina Sousa, Pamela Lona, Ana Lima, André Meneses, Sónia Campos. Revista Lusófona de Ciência e Medicina Veterinária, v. 20 (2026), IV Encontro de Investigação da FMV da Universidade Lusófona- Edição Especial, pp. 35..
Lima, Ana. (2026). - Antimicrobial Peptides As Sustainable Food Safety Alternatives. Tomás Moita, Adriana Belas, Laurentina Pedroso, Ana Lima, Isabel Santos. Revista Lusófona de Ciência e Medicina Veterinária, v. 20 (2026), IV Encontro de Investigação da FMV da Universidade Lusófona- Edição Especial, pp. 37..
Lima, Ana. (2026). Estudo preliminar de novos marcadores inflamatórios em cavalos hospitalizados: IL6 e MMP9. Tomás Casqueiro, José Prazeres, Gesiane Ribeiro, Ana Lima, Filipe R. Ramos, Tiago Mendonça. Revista Lusófona de Ciência e Medicina Veterinária, v. 20 (2026), IV Encontro de Investigação da FMV da Universidade Lusófona- Edição Especial, pp. 14. https://doi.org/10.60543/rlcmv.v20i.11091.
Lima, Ana. (2025). -A novel way for whey: a life’s work. Revista Lusófona de Ciência e Medicina Veterinária, v. 18 (2025), p.8. .
Lima, Ana. (2025). Opuntia cladodes antibacterial activities: potential for mastitis, Revista Lusófona de Ciência e Medicina Veterinária, v. 18 (2025), p. 32. .
Lima, Ana. (2026). Potential health benefits of cardoon in cheese production. Revista Lusófona de Ciência e Medicina Veterinária, v. 15 (2024), p.20. .
Lima, Ana. (2024). Acrylamide levels in chips: are potato chips the only “bad guys”? Revista Lusófona de Ciência e Medicina Veterinária, v. 15 (2024), p.39. .
Palma, Patrícia; Fialho, Sofia; Lima, Ana; Novais, Maria Helena; Costa, Maria João; Montemurro, Nicola; Pérez, Sandra; Lopez de Alda, Miren. (2020). Pharmaceuticals in a Mediterranean Basin: The influence of temporal and hydrological patterns in environmental risk assessment. https://www.sciencedirect.com/science/article/pii/S0048969719362011
Tomaz, Alexandra; Palma, Patrícia; Fialho, Sofia; Lima, Ana; Alvarenga, Paula; Potes, Miguel; Costa, Maria João; Salgado, Rui. (2020). Risk assessment of irrigation-related soil salinization and sodification in Mediterranean areas. http://hdl.handle.net/10400.5/20796
Palma, Patrícia; Penha, Alexandra Marchã; Novais, Maria Helena; Fialho, Sofia; Lima, Ana; Mourinha, Clarisse; Alvarenga, Paula; et al. (2021). Water-Sediment Physicochemical Dynamics in a Large Reservoir in the Mediterranean Region under Multiple Stressors. http://dx.doi.org/10.3390/w13050707
Palma, Patrícia; Fialho, Sofia; Lima, Ana; Mourinha, Clarisse; Penha, Alexandra; Novais, Maria Helena; Rosado, Anabela; et al. (2020). Land-Cover Patterns and Hydrogeomorphology of Tributaries: Are These Important Stressors for the Water Quality of Reservoirs in the Mediterranean Region?. http://dx.doi.org/10.3390/w12102665
Palma, Patrícia; Penha, Alexandra Marchã; Novais, Maria Helena; Fialho, Sofia; Lima, Ana; Catarino, Adriana; Mourinha, Clarisse; et al. (2023). Integrative toolbox to assess the quality of freshwater sediments contaminated with potentially toxic metals. http://dx.doi.org/10.1016/j.envres.2022.114798
Tomaz, Alexandra; Fialho, Sofia; Lima, Ana; Penha, Alexandra; Novais, Helena; Potes, Miguel; Yakunin, M.; et al. (2018). Contribution to the salinization risk assessment, under drought conditions, in the Alqueva irrigation area (South Portugal).
Tomaz, Alexandra; Fialho, Sofia; Lima, Ana; Alvarenga, Paula; Potes, Miguel; Salgado, Rui; Palma, Patrícia. (2018). Avaliação da qualidade da água de rega e do risco de salinização do solo em condições de seca: o caso do perímetro de Alqueva em 2017.
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